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Tetracycline Linked to Teeth Staining

Pit-and-Fissure Sealants Developed

In the 1960s, E.I. Cueto created the first pit-and-fissure sealant material intended for caries prevention. However, the sealant showed bacterial disintegration over time so it was never released on the public market. Over the next few years, with the help of Buonocore, a more successful sealant would be created and released to the public.

PFM Porcelains Developed

Dr. Rafael L. Bowen, director of the American Dental Association Health Foundation (ADAHF) Paffenbarger Research Center (PRC) at NBS, consults with a volunteer patient in the center’s 5-year clinical trial of an adhesive material to bond composite restorations to dentin and enamel. Bowen, who invented a dental resin known as BIS-GMA, also is developing glass inserts for composite restorations which will improve their wear resistance and reduce leakage around such restorations.

First Composite Formulations Based on Bowen Formula