Pit-and-Fissure Sealants Developed
In the 1960s, E.I. Cueto created the first pit-and-fissure sealant material intended for caries prevention. However, the sealant showed bacterial disintegration over time so it was never released on the public market. Over the next few years, with the help of Buonocore, a more successful sealant would be created and released to the public.